The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

Apr. 20, 2017
Applicants:

Les Laboratoires Servier, Suresnes, FR;

Vernalis (R&d) Ltd, Winnersh, GB;

Inventors:

András Kotschy, Törökbálint, HU;

Zoltán Szlávik, Budapest, HU;

Márton Csékei, Dunakeszi, HU;

Attila Paczal, Budapest, HU;

Zoltán Szabó, Budapest, HU;

Szabolcs Sipos, Budapest, HU;

Gábor Radics, Erd, HU;

Ágnes Proszenyák, Molnári, HU;

Balázs Bálint, Fót, HU;

Alain Bruno, Paris, FR;

Olivier Geneste, Rueil-Malmaison, FR;

James Edward Paul Davidson, Great Shelford, GB;

James Brooke Murray, Linton, GB;

I-Jen Chen, Cambridge, GB;

Françoise Perron-Sierra, Paris, FR;

Assignees:

LES LABORATOIRES SERVIER, Suresnes, FR;

VERNALIS (R&D) LTD, Winnersh Berkshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 495/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/538 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/538 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); C07D 495/04 (2013.01);
Abstract

Compounds of formula (I): wherein R, R, R, R, R, R, R, R, X, A and n are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.


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