The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Apr. 08, 2016
Applicant:

The Curators of the University of Missouri, Columbia, MO (US);

Inventors:

Mahmoud Almasri, Columbia, MO (US);

Shibajyoti Ghosh Dastider, Columbia, MO (US);

Shuping Zhang, Columbia, MO (US);

Majed El Dweik, Jefferson City, MO (US);

Nuh Sadi Yuksek, Columbia, MO (US);

Ibrahem Jasim, Columbia, MO (US);

Jiayu Liu, Columbia, MO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); B03C 5/00 (2006.01); G01N 33/543 (2006.01); B01L 3/00 (2006.01); B03C 5/02 (2006.01); G01N 27/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56916 (2013.01); B01L 3/502761 (2013.01); B03C 5/005 (2013.01); B03C 5/026 (2013.01); G01N 33/5438 (2013.01); B01L 3/502707 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0887 (2013.01); B01L 2400/0424 (2013.01); B03C 2201/26 (2013.01); G01N 27/06 (2013.01); G01N 2333/245 (2013.01); G01N 2333/255 (2013.01);
Abstract

Disclosed herein are example embodiments of a transformative sensor apparatus that is capable of detecting and quantifying the presence of a substance of interest such as a specified bacteria within a sample via changes in impedance exhibited by a detection electrode array. In an example embodiment, sensitivity is improved by including a focusing electrode array in a rampdown channel to focus a concentration of the substance of interest into a detection region. The focusing electrodes include an opposing pair of electrodes in a rampdown orientation. The focusing electrode may also include tilted thin film finger electrodes extending from the rampdown electrodes. In another example embodiment, trapping electrodes are positioned to trap a concentration of the substance of interest onto the detection electrode array.


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