The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2019
Filed:
Mar. 08, 2013
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Ghyslain Budin, Boston, MA (US);
Ralph Weissleder, Peabody, MA (US);
Hakho Lee, Acton, MA (US);
Hyun Jung Chung, Cambridge, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B82Y 30/00 (2011.01); G01N 33/569 (2006.01); G01N 33/58 (2006.01); G01N 24/08 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56911 (2013.01); B82Y 30/00 (2013.01); G01N 33/56938 (2013.01); G01N 33/56944 (2013.01); G01N 33/585 (2013.01); G01N 24/08 (2013.01); G01N 2458/00 (2013.01);
Abstract
The present invention provides novel methods of magnetically labeling a bacterial cell by contacting the call with an affinity ligand and subsequently contacting the cell with a magnetic agent, where the affinity ligand and magnetic agent include bioorthogonally reactive groups that can react with each other to form a covalent bond. Compounds, compositions, kits and applications of the method are also described.