The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Mar. 10, 2016
Applicant:

Genia Technologies, Inc., Santa Clara, CA (US);

Inventors:

Randall W. Davis, Pleasanton, CA (US);

Edward Shian Liu, Saratoga, CA (US);

Eric Takeshi Harada, San Jose, CA (US);

Anne Aguirre, San Jose, CA (US);

Andrew Trans, Mt. View, CA (US);

James Pollard, Mt. View, CA (US);

Cynthia Cech, Newcastle, WA (US);

Hui Tian, Cupertino, CA (US);

Robert Yuan, San Jose, CA (US);

John Foster, Mt. View, CA (US);

Roger Chen, Saratoga, CA (US);

Assignees:

GENIA TECHNOLOGIES, INC., Santa Clara, CA (US);

ROCHE MOLECULAR SYSTEMS, INC., Pleasanton, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); C12Q 1/6869 (2018.01); C12M 1/34 (2006.01); G01N 33/487 (2006.01); G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C12M 1/34 (2013.01); G01N 27/3277 (2013.01); G01N 27/3278 (2013.01); G01N 27/44791 (2013.01); G01N 33/48721 (2013.01);
Abstract

A biochip for molecular detection and sensing is disclosed. The biochip includes a substrate. The biochip includes a plurality of discrete sites formed on the substrate having a density of greater than five hundred wells per square millimeter. Each discrete site includes sidewalls disposed on the substrate to form a well. Each discrete site includes an electrode disposed at the bottom of the well. In some embodiments, the wells are formed such that cross-talk between the wells is reduced. In some embodiments, the electrodes disposed at the bottom of the wells are organized into groups of electrodes, wherein each group of electrodes shares a common counter electrode. In some embodiments, the electrode disposed at the bottom of the well has a dedicated counter electrode. In some embodiments, surfaces of the sidewalls are silanized such that the surfaces facilitate the forming of a membrane in or adjacent to the well.


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