The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Dec. 20, 2016
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Ray Camphausen, Wayland, MA (US);

John O'Loughlin, Stow, MA (US);

Bernice Yeung, Lexington, MA (US);

Yihong Zhang, Acton, MA (US);

Assignee:

BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 14/78 (2006.01); A61K 39/395 (2006.01); C07K 14/435 (2006.01); C07K 14/525 (2006.01); C07K 14/715 (2006.01); C07K 14/71 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); C07K 16/18 (2013.01); A61K 38/00 (2013.01); C07K 14/71 (2013.01); C07K 14/7155 (2013.01); C07K 16/2863 (2013.01); C07K 2317/31 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2318/20 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.


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