The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

May. 18, 2016
Applicant:

Pieris Pharmaceuticals Gmbh, Freising-Weihenstephan, DE;

Inventors:

Marlon Hinner, Munich, DE;

Andrea Allersdorfer, Wolnzach, DE;

Rachida Siham Bel Aiba, Munich, DE;

Michaela Aloe, Freising, DE;

Alexander Wiedenmann, Ulm, DE;

Gabriele Matschiner, Munich, DE;

Martin Huelsmeyer, Roemerberg, FR;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); G01N 33/50 (2006.01); A61K 38/00 (2006.01); A61K 38/02 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4725 (2013.01); C12N 15/102 (2013.01);
Abstract

The present disclosure relates to novel, specific-binding therapeutic and/or diagnostic proteins directed against Glypican-3 (GPC3), which proteins preferably are muteins of a lipocalin protein, more preferably of lipocalin 2 (Lcn2 or NGAL). Present disclosure also relates to nucleic acid molecules encoding such proteins and to methods for generation and use of such proteins and nucleic acid molecules. Accordingly, present disclosure also is directed to pharmaceutical and/or diagnostic compositions comprising such lipocalin proteins, including uses of these proteins.


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