The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Jun. 15, 2017
Applicant:

Janssen Vaccines & Prevention B.v., Leiden, NL;

Inventors:

Thierry-Thien Nguyen, Wilmington, DE (US);

Mark Bruner, Norristown, PA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); A61K 39/12 (2006.01); A61K 39/21 (2006.01); A61K 39/38 (2006.01); C07K 14/16 (2006.01); C12N 15/09 (2006.01); A61K 31/047 (2006.01); A61K 31/198 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 31/047 (2013.01); A61K 31/198 (2013.01); A61K 39/12 (2013.01); A61K 39/21 (2013.01); A61K 39/38 (2013.01); C07K 14/16 (2013.01); C12N 15/09 (2013.01); A61K 39/00 (2013.01); A61K 2039/525 (2013.01); A61K 2039/55505 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01);
Abstract

Immunogenic compositions containing a human immunodeficiency virus (HIV) gp140 protein, sorbitol, polysorbate 20, and histidine buffer are described. The described immunogenic compositions are advantageous in that they are stable at refrigerated temperature for extended periods of time, and are compatible with an adjuvant. Also described are methods of using the immunogenic compositions to induce an immune response against an HIV in a subject. The immunogenic compositions can be administered alone, or in combination with one or more additional HIV antigens, or one or more adenovirus vectors encoding the one or more additional HIV antigens.


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