The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2019
Filed:
Jun. 24, 2016
Kadmon Corporation Llc, New York, NY (US);
Kellen L. Olszewski, Brooklyn, NY (US);
Ji-In Kim, Princeton, NJ (US);
Masha V. Poyurovsky, New York, NY (US);
Kevin G. Liu, West Windsor, NJ (US);
Anthony Barsotti, New York, NY (US);
Koi Morris, Plainsboro, NJ (US);
Kadmon Corportion, LLC, New York, NY (US);
Abstract
Provided herein are compounds that modulate glucose uptake activity and are useful for treating cancer, autoimmune diseases, inflammation, infectious diseases, and metabolic diseases. In certain embodiments, the compounds modulate glucose uptake activity by modulating cellular components, including, but not limited to those related to glycolysis and known transporters/co-transporters of glucose such as GLUT1 and other GLUT family members/alternative hexose transporters. In certain embodiments, the compounds have the structure of formula I: Formula (I) wherein the variables have the values disclosed herein.