The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

May. 13, 2016
Applicant:

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Haitao Ji, Salt Lake City, UT (US);

Yongqiang Zhang, Salt Lake City, UT (US);

Min Zhang, Salt Lake City, UT (US);

Jonathan L. Catrow, Salt Lake City, UT (US);

Assignee:

UNIVERSITY OF UTAH RESEARCH FOUNDATION, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/14 (2006.01); A61P 43/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 498/14 (2013.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01);
Abstract

In one aspect, the invention relates to substituted 5H-[1,2,5]oxadiazolo [3',4′:5,6]pyrazino[2,3-b]indole analogs, derivatives thereof, and related compound; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and A methods of treating disorders, e.g., various tumors and cancers, associated with a β-catenin/T-cell factor interaction dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


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