The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2019
Filed:
Jun. 02, 2014
Applicant:
Emory University, Atlanta, GA (US);
Inventors:
Stephen F. Traynelis, Decatur, GA (US);
Dennis C. Liotta, Atlanta, GA (US);
Rose M. Santangelo, Decatur, GA (US);
Ethel C. Garnier, Tucker, GA (US);
Assignee:
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 217/16 (2006.01); C07D 491/056 (2006.01); C07D 409/06 (2006.01); C07D 405/06 (2006.01); C07D 401/06 (2006.01); C07D 413/06 (2006.01); C07D 409/04 (2006.01); C07D 401/04 (2006.01); C07D 277/34 (2006.01); C07D 263/58 (2006.01); C07D 239/88 (2006.01); C07D 215/22 (2006.01); C07D 209/08 (2006.01);
U.S. Cl.
CPC ...
C07D 217/16 (2013.01); C07D 209/08 (2013.01); C07D 215/22 (2013.01); C07D 239/88 (2013.01); C07D 263/58 (2013.01); C07D 277/34 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 405/06 (2013.01); C07D 409/04 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01); C07D 491/056 (2013.01);
Abstract
Provided are compounds, pharmaceutical compositions and methods of treating or preventing disorders associated with NMDA receptor activity, including schizophrenia, Parkinson's disease, cognitive disorders, depression, neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds of the general Formulas A-J, and pharmaceutically acceptable salts, esters, prodrugs or derivatives thereof are disclosed.