The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Sep. 06, 2013
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);

Inventors:

Manu Prakash, San Francisco, CA (US);

George Korir, Stanford, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 9/00 (2006.01); G06K 21/02 (2006.01); B01L 3/00 (2006.01); G05B 19/14 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/50273 (2013.01); B01L 3/502738 (2013.01); B01L 9/527 (2013.01); G05B 19/14 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/12 (2013.01); B01L 2300/123 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0655 (2013.01); G06K 21/02 (2013.01); Y10T 436/2575 (2015.01);
Abstract

Techniques are provided for a completely programmable fluidic manipulation without requiring any external control elements or electricity. A chip includes multiple microfluidic channels separated from an outside of the chip by an outer flexible substrate. An apparatus includes a plurality of actuators rotatably connected to a support structure with a recess for receiving the chip. Each actuator includes a plurality of teeth protruding outward, and is positioned so that at least in some angle of rotation a tooth of the actuator extends sufficiently into the recess to compress a microfluidic channel in a chip disposed in the recess. An optional punch card guide is included for guiding a card to contact the actuators. A system or kit includes a punch card on which is formed a plurality of punch features, each configured to engage a tooth of an actuator. Different microfluidic protocols are executed by simply changing the punch card.


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