The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Apr. 18, 2016
Applicant:

The Research Foundation for the State University of New York, Buffalo, NY (US);

Inventors:

Jonathan Lovell, Niagara Falls, CA;

Shuai Shao, Tonawanda, NY (US);

Jumin Geng, Williamsville, NY (US);

Wei-Chiao Huang, Amherst, NY (US);

Shwu-Maan Lee, Rockville, MD (US);

Charles Richter King, Washington, DC (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/69 (2017.01); A61K 38/41 (2006.01); A61K 9/127 (2006.01); C07K 14/795 (2006.01); A61K 38/16 (2006.01); A61K 47/54 (2017.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/6911 (2017.08); A61K 9/127 (2013.01); A61K 38/162 (2013.01); A61K 38/41 (2013.01); A61K 47/544 (2017.08); B82Y 5/00 (2013.01); C07K 14/795 (2013.01); C07K 2319/21 (2013.01);
Abstract

The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual.


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