The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Jul. 02, 2015
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Hugh Smyth, Austin, TX (US);

Ju Du, Austin, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/60 (2017.01); A61K 31/7036 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 31/7036 (2013.01); A61K 45/06 (2013.01); Y02A 50/473 (2018.01); Y02A 50/475 (2018.01); Y02A 50/478 (2018.01); Y02A 50/481 (2018.01);
Abstract

In some aspects, pegylated aminoglycoside compounds are provided. In some embodiments, m-PEG-tobramycin compounds may be used to treat a biofilm infection or reduce or treat established biofilms. The present invention provides, in various aspects, compounds and methods for the treatment of infections, such as biofilm infections or chronic biofilm infections. The chronic biofilm infection may occur in wounds, implanted devices, immunocompromised patients, people with cystic fibrosis, eye infections, etc.


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