The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2019

Filed:

Jun. 25, 2010
Applicants:

Manon Couture, St-Augustin-de-Desmaures, CA;

Michele Dargis, Quebec, CA;

Pierre-olivier Lavoie, Quebec, CA;

Louis-philippe Vezina, Neuville, CA;

Marc-andre D'aoust, Quebec, CA;

Inventors:

Manon Couture, St-Augustin-de-Desmaures, CA;

Michele Dargis, Quebec, CA;

Pierre-Olivier Lavoie, Quebec, CA;

Louis-Philippe Vezina, Neuville, CA;

Marc-Andre D'Aoust, Quebec, CA;

Assignee:

MEDICAGO INC., Quebec, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); C07K 14/11 (2006.01); C12N 15/09 (2006.01); C12N 15/82 (2006.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01); C12N 15/8257 (2013.01); A61K 2039/5258 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16123 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16222 (2013.01); C12N 2760/16223 (2013.01); C12N 2760/16234 (2013.01);
Abstract

A method for synthesizing chimeric influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of chimeric influenza HA in a plant or a portion of a plant. The invention is also directed towards a VLP comprising chimeric influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding chimeric influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines.


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