The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2019
Filed:
Dec. 12, 2011
William Tao Shi, Briarcliff Manor, NY (US);
Ladislav Jankovic, Fishkill, NY (US);
William Tao Shi, Briarcliff Manor, NY (US);
Ladislav Jankovic, Fishkill, NY (US);
KONINKLIJKE PHILIPS N.V., Eindhoven, NL;
Abstract
Bubbles (-) are utilized in some embodiments as part of a photoacoustic contrast agent () and, in some embodiments, to localize one or more locations (-) of a source of acoustic energy. The bubbles, such as microbubbles, can be used in proximity of nanoparticles of a first photoacoustic contrast agent, thereby affording a second photoacoustic contrast agent. The bubbles can intercept and re-radiate acoustic energy emitted by light-based activation of the first photoacoustic contrast agent in the immediate vicinity of the bubbles. As a further option, if the nanoparticles permeate further to tissue structures but remain in close enough proximity, their positions can be triangulated by the nearby bubbles, based on direction (-) and time delays (-) of ultrasound received by a transducer array.