The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2019

Filed:

Mar. 29, 2018
Applicant:

The Procter & Gamble Company, Cincinnati, OH (US);

Inventors:

John Christian Haught, West Chester, OH (US);

Sancai Xie, Liberty Township, OH (US);

Benjamin Thomas Circello, Maineville, OH (US);

Cheryl Sue Tansky, Forest Park, OH (US);

Malgorzata Klukowska, Mason, OH (US);

Thomas Glenn Huggins, Mason, OH (US);

Deepa Ashok Khambe, Cincinnati, OH (US);

Donald James White, Fairfield, OH (US);

Assignee:

The Procter & Gamble Company, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); G01N 33/566 (2006.01); G01N 33/50 (2006.01); C12Q 1/6897 (2018.01); G01N 33/579 (2006.01); A61K 8/02 (2006.01); A61K 8/21 (2006.01); A61K 8/36 (2006.01); A61K 8/39 (2006.01); A61K 8/42 (2006.01); A61K 8/49 (2006.01); A61Q 11/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/566 (2013.01); A61K 8/0204 (2013.01); A61K 8/21 (2013.01); A61K 8/361 (2013.01); A61K 8/39 (2013.01); A61K 8/42 (2013.01); A61K 8/4926 (2013.01); A61Q 11/00 (2013.01); C12Q 1/6897 (2013.01); G01N 33/5041 (2013.01); G01N 33/5044 (2013.01); G01N 33/5091 (2013.01); G01N 33/579 (2013.01); A61K 2800/74 (2013.01); C12Q 2600/136 (2013.01); G01N 2333/195 (2013.01); G01N 2333/705 (2013.01); G01N 2333/70596 (2013.01); G01N 2400/50 (2013.01);
Abstract

Methods for detecting and quantifying toxins present in the oral cavity. The methods may include providing a biological sample, providing reporter cells expressing one or more Toll like receptors, exposing the cells to the biological sample, measuring the EC50 value of the lipopolysaccharide on activation of a Toll like receptor, quantification of the lipopolysaccharide in the biological sample.


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