The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2019
Filed:
Nov. 28, 2017
Applicant:
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Inventors:
Chang-Soo Lee, Daejeon, KR;
Chul Soon Park, Daejeon, KR;
Oh Seok Kwon, Daejeon, KR;
Tai Hwan Ha, Daejeon, KR;
Assignee:
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, Daejeon, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/06 (2006.01); G01N 21/64 (2006.01); C12N 9/18 (2006.01); C07D 209/10 (2006.01); C07D 311/80 (2006.01); C09K 11/06 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6486 (2013.01); C07D 209/10 (2013.01); C07D 311/80 (2013.01); C09K 11/06 (2013.01); C12N 9/18 (2013.01); C12Y 301/03001 (2013.01); C09K 2211/1007 (2013.01); C09K 2211/1029 (2013.01); C09K 2211/1088 (2013.01);
Abstract
A near-infrared fluorescent probe for detecting ALP is represented by Chemical 1. The fluorescent probe capable of detecting ALP can selectively detect ALP only quickly and accurately. In addition, the fluorescent probe allows monitoring of a biological phenomenon occurring in cells and tissues through noninvasive in-vivo imaging and during the early osteogenic differentiation in real time.