The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2019
Filed:
Jan. 20, 2016
Applicant:
Affymetrix, Inc., Santa Clara, CA (US);
Inventors:
Quan Nguyen, San Ramon, CA (US);
Yunqing Ma, San Jose, CA (US);
Audrey Lin, San Jose, CA (US);
Shauna Levinson, Los Gatos, CA (US);
Chunfai Lai, Fremont, CA (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07H 21/00 (2006.01); C12Q 1/6841 (2018.01); C12Q 1/6816 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6841 (2013.01); C12Q 1/6816 (2013.01);
Abstract
This invention provides compositions, methods, and systems for characterizing, resolving, and quantitating single stranded and double stranded DNA and RNA in-situ. Paired sense and anti-sense probes can signal the presence of double stranded nucleic acids. DNA and RNA can be distinguished in cell and tissue samples by hybridizing with probe sets adapted to highlight differences in these targets in-situ.