The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2019

Filed:

Dec. 21, 2012
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Long Cai, Port Jefferson Station, NY (US);

Eric Lubeck, Pasadena, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6809 (2018.01); C12Q 1/6841 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6809 (2013.01); C12Q 1/6841 (2013.01);
Abstract

Methods and systems are provided for creating molecular barcodes or indicia for cellular constituents within single cells and for resolving such barcodes or indicia with super-resolution technologies such as super-resolution microscopy. By this approach, numerous molecular species that can be measured simultaneously in single cells. It has been demonstrated that multiple mRNA transcripts can be labeled with a spatially ordered sequence of fluorophores, and that barcodes can be resolved. In addition, alternative splicing events can be characterized by identifying and quantifying mRNA isoforms in an individual cell.


Find Patent Forward Citations

Cai, Long. (2019). Multiplex detection of molecular species in cells by super-resolution imaging and combinatorial labeling (U.S. Patent No. 10266876). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10266876

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…