The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2019
Filed:
Nov. 23, 2016
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Michael Sweredoski, Altadena, CA (US);
Annie Moradian, La Canada, CA (US);
Tanya R. Yakushi, Monterey Park, CA (US);
Sonja Hess, Arcadia, CA (US);
Roxana Eggleston-Rangel, Los Angeles, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/00 (2006.01); C12P 21/02 (2006.01); C12N 9/02 (2006.01); C12N 11/08 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C12N 9/0051 (2013.01); C12N 11/08 (2013.01); C12Y 108/04011 (2013.01); C12Y 108/04012 (2013.01);
Abstract
A method for preparing a methionine containing peptide or protein for analysis by mass spectrometry by incubating the methionine containing peptide or protein with a heterologous methionine sulfoxide reductase A (MsrA), a heterologous methionine sulfoxide reductase B (MsrB), or a heterologous methionine sulfoxide reductase AB (MsrAB) enzyme results in the reduction of an oxidized methionine containing peptide or protein.