The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2019
Filed:
Jun. 26, 2015
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Southern Research Institute, Birmingham, AL (US);
Rudolph Juliano, Chapel Hill, NC (US);
William P. Janzen, Chapel Hill, NC (US);
Joseph A. Maddry, Birmingham, AL (US);
Canhong Cao, Chapel Hill, NC (US);
Xin Ming, Chapel Hill, NC (US);
Bing Yang, Chapel Hill, NC (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Southern Research Institute, Birmingham, AL (US);
Abstract
Methods of administering an oligonucleotide of interest into a cell in vitro or in vivo are described. In the methods, a small organic compound active agent is concurrently administered to the cell in an amount effective to increase the delivery of the oligonucleotide into the cell, and/or increase the activity of said oligonucleotide in the cell. Compositions useful for carrying out the method are also described.