The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2019

Filed:

Jul. 22, 2016
Applicants:

Nexgen Biotechnologies, Inc., Seoul, KR;

Sun Kyo Lee, Gyeonggi-do, KR;

Inventors:

Sun Kyo Lee, Gyeonggi-do, KR;

Han Bong Ryu, Seoul, KR;

Seong Ran Lee, Gyeonggi-do, KR;

Jong Nam Choi, Gyeonggi-do, KR;

Tae Won Choi, Seoul, KR;

Tae Hyun Kim, Gyeonggi-do, KR;

Tae Hwa Jeong, Gyeonggi-do, KR;

Hyeong Il Kwon, Seoul, KR;

Assignees:

NEXGEN BIOTECHNOLOGIES, INC., Seoul, KR;

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/52 (2006.01); C07K 14/485 (2006.01); C12N 15/62 (2006.01); A61K 8/66 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01); C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
C12N 9/52 (2013.01); A61K 8/66 (2013.01); A61Q 19/00 (2013.01); A61Q 19/08 (2013.01); C07K 14/485 (2013.01); C12N 15/62 (2013.01); C12N 15/70 (2013.01); C12Y 304/24069 (2013.01); C07K 2319/55 (2013.01);
Abstract

A botulinum toxin-human epidermal growth factor fusion protein with increased skin cell proliferation and anti-oxidation effect has the amino acid sequence of SEQ ID NO: 2, a gene consisting of() codon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the botulinum toxin-human epidermal growth factor fusion protein, a recombinant vector including the gene, a host cell transformed with the recombinant vector, and a method for producing a botulinum toxin-human epidermal growth factor fusion protein by transforming a host cell with the recombinant vector, and a cosmetic composition for regenerating skin and improving skin wrinkle including, as an effective component, a botulinum toxin-human epidermal growth factor fusion protein, and as the cosmetic composition has an effect of regenerating skin and improving skin wrinkle, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery.


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