The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2019
Filed:
Aug. 07, 2015
Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, CN;
Hefei Cosource Pharmaceutical Co., Ltd., Hefei, Anhui, CN;
Jing Liu, Anhui, CN;
Qingsong Liu, Anhui, CN;
Xixiang Li, Anhui, CN;
Aoli Wang, Anhui, CN;
Hong Wu, Anhui, CN;
Cheng Chen, Anhui, CN;
Wenchao Wang, Anhui, CN;
Chen Hu, Anhui, CN;
Zheng Zhao, Anhui, CN;
Jiaxin Wu, Anhui, CN;
Juan Liu, Anhui, CN;
Kailin Yu, Anhui, CN;
Wei Wang, Anhui, CN;
Li Wang, Anhui, CN;
Beilei Wang, Anhui, CN;
HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES, Hefei, Anhui, CN;
HEFEI COSOURCE PHARMACEUTICAL CO., LTD., Hefei, Anhui, CN;
Abstract
Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases).