The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2019

Filed:

Jan. 04, 2018
Applicants:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Calitor Sciences, Llc, Newbury Park, CA (US);

Inventors:

Ning Xi, Newbury Park, CA (US);

Minxiong Li, Guangdong, CN;

Xiaobo Li, Guangdong, CN;

Wuhong Chen, Guangdong, CN;

Tao Zhang, Guangdong, CN;

Haiyang Hu, Guangdong, CN;

Weilong Dai, Guangdong, CN;

Yanjun Wu, Guangdong, CN;

Assignees:

CALITOR SCIENCES, LLC, Newbury Park, CA (US);

SUNSHINE LAKE PHARMA CO., LTD., Dongguan, Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01);
Abstract

The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.


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