The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2019
Filed:
Jun. 16, 2017
Pfizer Inc., New York, NY (US);
John Robert Springer, Wentzville, MO (US);
Balekudru Devadas, Chesterfield, MO (US);
Danny James Garland, House Springs, MO (US);
Margaret Lanahan Grapperhaus, Troy, IL (US);
Seungil Han, Mystic, CT (US);
Susan Landis Hockerman, Kirkwood, MO (US);
Robert Owen Hughes, Newtown, CT (US);
Eddine Saiah, Brookline, MA (US);
Mark Edward Schnute, Acton, MA (US);
Shaun Raj Selness, Chesterfield, MO (US);
Daniel Patrick Walker, Augusta, MO (US);
Zhao-Kui Wan, Lexington, MA (US);
Li Xing, Lexington, MA (US);
Christoph Wolfgang Zapf, Marlborough, MA (US);
Michelle Ann Schmidt, Millstadt, IL (US);
Pfizer Inc., New York, NY (US);
Abstract
Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (BTK). Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the BTK inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseeases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.