The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2019

Filed:

Jun. 27, 2017
Applicant:

Hitgen Ltd, Chengdu, CN;

Inventors:

Jin Li, Chengdu, CN;

Dengfeng Dou, Chengdu, CN;

Jinqiao Wan, Chengdu, CN;

Fei Pan, Chengdu, CN;

Peng Lv, Chengdu, CN;

Assignee:

HitGen LTD, Chengdu, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/48 (2006.01); A61K 31/40 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 207/48 (2013.01); A61K 31/40 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01);
Abstract

The present invention discloses a pyrrolic amide compound shown as a formula I, or crystal forms thereof, and pharmaceutically acceptable salts, hydrates or solvates, wherein Ris selected from hydrogen, hydroxyl, cyano, halogen, carboxyl, C-Calkyl and the like; Ris selected from hydrogen, hydroxyl, cyano, halogen and the like; Ris selected from hydroxyl and the like; X is selected from group, m is equal to 0, 1, 2 or 3, and n is equal to 0, 1 or 2. The novel compound shown as the formular I provided by the present invention has high deacetylase inhibitory viability; and meanwhile, a method for preparing the novel compound in the present invention has the advantages of fewer steps, simple and convenient operation, safety, environment friendliness, high yield and the like and is very suitable for industrial application.


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