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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10265410 B1

PDFFull Text
Date of Patent:
Apr. 23, 2019

Filed:

Apr. 15, 2016

Adverse side-effects associated with administration of an anti-hyaluronan agent and methods for ameliorating or preventing the side-effects

Applicant:

Halozyme, Inc., San Diego, CA (US);

Inventors:

Harold Michael Shepard, San Diego, CA (US);

Curtis Thompson, Encinitas, CA (US);

Xiaoming Li, San Diego, CA (US);

Gregory I. Frost, Palm Beach, FL (US);

Assignee:

Halozyme, Inc., San Diego, CA (US);

Attorneys:

Dentons US LLP

Stephanie Seidman

Primary Examiner:

Renee Claytor

Assistant Examiner:

Trent R Clarke

Int. Cl.
CPC ...
A61K 38/47 (2006.01); A61K 47/60 (2017.01); A61K 31/37 (2006.01); A61K 31/42 (2006.01); A61K 31/573 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/37 (2013.01); A61K 31/42 (2013.01); A61K 31/573 (2013.01); A61K 38/47 (2013.01); C12Y 302/01035 (2013.01);
Abstract

Provided herein are methods for ameliorating an adverse effect of systemic administration of a PEG hyaluronan degrading enzyme to a subject. The methods involve systemically administering a PEGylated hyaluronan degrading enzyme, particularly a PEGylated hyaluronidase, such as any of the animal or bacterial hyaluronidases, to the subject and administering an amount of a corticosteroid sufficient to ameliorate the adverse effect. Also provided are method of treating a hyaluronan-associated disease or condition for single-agent therapy or combination therapy.

Find Patent Forward Citations

Shepard, Harold. (2019). Adverse side-effects associated with administration of an anti-hyaluronan agent and methods for ameliorating or preventing the side-effects (U.S. Patent No. 10265410). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10265410

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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