The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2019
Filed:
Nov. 17, 2015
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Nicholas A. Peppas, Austin, TX (US);
Sarena D. Horava, Austin, TX (US);
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 9/00 (2006.01); A61K 38/48 (2006.01); A61K 47/60 (2017.01); A61K 47/58 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48176 (2013.01); A61K 9/0053 (2013.01); A61K 38/4846 (2013.01); A61K 47/58 (2017.08); A61K 47/60 (2017.08); A61K 47/6903 (2017.08); C12Y 304/21022 (2013.01);
Abstract
In some aspects, a composition comprising a pH-sensitive crosslinked copolymer of methacrylic acid and poly(ethylene glycol) monomethyl ether methacrylate and a therapeutic protein is provided. In some embodiments, the therapeutic protein is a high molecular weight protein such as factor VIII or factor IX. In some embodiments, the composition is orally administered to a patient to treat a disease or disorder such as, e.g., hemophilia.