The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2019

Filed:

Jun. 21, 2018
Applicant:

Cleveland Biolabs, Inc., Buffalo, NY (US);

Inventors:

Anatoli Gleiberman, East Aurora, NY (US);

Lyudmila Burdelya, Lancaster, NY (US);

Andrei Gudkov, East Aurora, NY (US);

Assignee:

CLEVELAND BIOLABS, INC., Buffalo, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/195 (2006.01); C07K 14/255 (2006.01); A61K 38/16 (2006.01); A61K 39/02 (2006.01); A61K 39/112 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 38/164 (2013.01); A61K 39/39533 (2013.01); A61K 39/39558 (2013.01); C07K 14/195 (2013.01); C07K 14/255 (2013.01); C07K 16/2878 (2013.01); A61K 39/02 (2013.01); A61K 39/0275 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/545 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01); A61K 2039/585 (2013.01); C07K 14/705 (2013.01);
Abstract

The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor agonist such as flagellin. The present invention also relates to protecting the liver from a liver toxicity using a Toll-like receptor agonist.


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