The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2019
Filed:
Jun. 16, 2014
Applicant:
Viratherapeutics Gmbh, Innsbruck, AT;
Inventors:
Dorothee Von Laer, Innsbruck, AT;
Tsanan Heimann, Mainz, DE;
Assignee:
VIRATHERAPEUTICS GMBH, Innsbruck, AT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/766 (2015.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
A61K 35/766 (2013.01); C12N 9/1211 (2013.01); C12Y 207/01021 (2013.01); C12N 2760/20232 (2013.01); C12N 2760/20243 (2013.01); C12N 2810/6072 (2013.01);
Abstract
Embodiments of the present invention relate to compositions and methods for producing recombinant VSV viruses. In accordance with these embodiments, viral vectors can include a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV. Other embodiments relate to cells for producing a LCMV-GP-pseudotyped VSV vectors. Embodiments also relate to the use of the vectors and cells as part of a pharmaceutical composition for the treatment of solid tumors.