The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

May. 16, 2016
Applicant:

Lumiradx Uk Ltd., London, GB;

Inventors:

Phillip Lowe, Tullibody, GB;

Steven Alexander Keatch, Stirling, GB;

Brian McGuigan, Stirling, GB;

Assignee:

LUMIRADX UK LTD, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); C12Q 1/00 (2006.01); B01L 3/00 (2006.01); G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5438 (2013.01); B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); C12Q 1/001 (2013.01); C12Q 1/006 (2013.01); C12Y 101/03004 (2013.01); G01N 27/3277 (2013.01); G01N 33/54326 (2013.01); G01N 33/54366 (2013.01); B01L 2200/04 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/161 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0688 (2013.01); G01N 2333/904 (2013.01);
Abstract

A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.


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