The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2019
Filed:
Feb. 24, 2015
Applicant:
Novogy, Inc., Cambridge, MA (US);
Inventors:
Elena E. Brevnova, Belmont, MA (US);
Arthur J. Shaw, IV, Belmont, MA (US);
Emily H. Greenhagen, Melrose, MA (US);
Assignee:
NOVOGY, INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 9/10 (2006.01); C12P 7/64 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1029 (2013.01); C12P 7/6445 (2013.01); C12Y 203/0102 (2013.01);
Abstract
DGA1 catalyzes the final enzymatic step for converting acyl-CoA and 1,2-diacylglycerol to triacylglycerols (TAG) and CoA in yeast. Disclosed are methods for expression in an oleaginous yeast host of polynucleotide sequences encoding DGA1 from, or. Also described herein are engineered recombinant host cells ofcomprising heterologous DGA1 polynucleotides encoding DGA1 proteins, or functionally active portions thereof, having the capability of producing increased lipid production and possessing the characteristic of enhanced glucose consumption efficiency.