The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2019
Filed:
Oct. 09, 2018
Applicant:
Cellerant Therapeutics, Inc., San Carlos, CA (US);
Inventors:
Timothy C. Fong, Moraga, CA (US);
Adrianus Geertrudis Wilhelmus Domen, Kansas City, KS (US);
Julie Lynne Christensen, Boulder Creek, CA (US);
Assignee:
CELLERANT THERAPEUTIC, INC., San Carlos, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/078 (2010.01); C12N 5/0789 (2010.01); A61K 9/10 (2006.01); A61K 35/15 (2015.01); A61K 35/28 (2015.01); A61K 9/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0647 (2013.01); A61K 9/0014 (2013.01); A61K 9/10 (2013.01); A61K 35/12 (2013.01); A61K 35/15 (2013.01); A61K 35/28 (2013.01); A61K 2035/124 (2013.01); C12N 2500/44 (2013.01); C12N 2500/90 (2013.01); C12N 2500/99 (2013.01); C12N 2501/125 (2013.01); C12N 2501/145 (2013.01); C12N 2501/22 (2013.01); C12N 2501/23 (2013.01); C12N 2501/2303 (2013.01); C12N 2501/26 (2013.01); C12N 2501/727 (2013.01);
Abstract
The present disclosure relates to a method of expanding myeloid progenitor cells by culturing an initial population of cells in a medium comprising a mixture of cytokines and growth factors that promote growth and expansion of the myeloid progenitor cells. The expanded cell population provides a source of cells as therapeutic treatments for neutropenia and/or thrombocytopenia arising in patients subjected to myeloablative therapy and hematopoietic stem cell transplantation.