The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2019
Filed:
Sep. 21, 2017
Yale University, New Haven, CT (US);
Ospedale San Raffaele Srl, Milan (MI), IT;
Fondazione Telethon, Rome, IT;
Richard A. Flavell, Guilford, CT (US);
Nicola Gagliani, New Haven, CT (US);
Silvia Gregori, Buccinasco, IT;
Samuel Huber, Hamburg, DE;
Chiara Francesca Magnani, Milan, IT;
Maria Grazia Roncarolo, Segrate, IT;
Yale University, New Haven, CT (US);
Ospedale San Raffaele S.r.l., Milan (MI), IT;
Fondazione Telethon, Rome (RM), IT;
Abstract
The invention is based upon the discovery that T regulatory type 1 (Tr1) cells express particular cell surface markers that allow for their selection, enrichment, isolation, purification and administration. The ability to use the particular markers described herein to select, enrich, isolate, purify and administer Tr1 cells allows for improved methods of Tr1 therapies for treating a wide variety of diseases and disorders.