The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2019
Filed:
Feb. 03, 2016
Applicant:
Medpacto Inc., Suwon-si, Gyeonggi-do, KR;
Inventors:
Il Ho Ha, Gunpo-si, KR;
Seok Ho Yoo, Daejeon, KR;
Hye Nan Kim, Seosan-si, KR;
Yeung Chul Kim, Daejeon, KR;
Ju Ry Lim, Daejeon, KR;
Assignee:
MEDPACTO INC., Suwon-si, Gyeonggi-Do, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); A61K 38/00 (2013.01); C07K 2319/21 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided are a modified DKK2 polypeptide according to an aspect, a nucleic acid encoding the same, a preparation method thereof, and use thereof. Accordingly, a modified DKK2 protein having an additional glycosyl group or improved binding affinity for a substrate LRP6 may be efficiently prepared, thereby being used for promoting angiogenesis or preventing or treating vascular permeability-related diseases.