The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

Dec. 23, 2015
Applicant:

Cephalon, Inc., Frazer, PA (US);

Inventors:

Shawn P. Allwein, Downingtown, PA (US);

Roger P. Bakale, San Diego, CA (US);

Dale R. Mowrey, Glenmoore, PA (US);

Daniel E. Petrillo, Doylestown, PA (US);

Sander Kluwer, Amsterdam, NL;

Assignee:

CEPHALON, INC., Frazer, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 241/04 (2006.01); C07D 295/135 (2006.01); C07D 403/12 (2006.01); A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
C07D 241/04 (2013.01); A61K 31/495 (2013.01); C07D 295/135 (2013.01); C07D 403/12 (2013.01);
Abstract

The present disclosure is directed to improved methods useful for the preparation of, for example, 2-[[5-chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5Hbenzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]-N-methyl-benzamide (CEP-37440).


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