The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

Aug. 14, 2017
Applicant:

University of East Anglia, Norwich, GB;

Inventors:

Sean Patrick Bew, Norwich, GB;

Sean Michael Thurston, Norwich, GB;

Paolo Pesce, Noicattaro, IT;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 203/02 (2006.01); C07D 203/14 (2006.01); C07D 203/18 (2006.01); C07D 203/22 (2006.01); B01J 31/02 (2006.01); C07D 203/08 (2006.01); C07D 403/04 (2006.01); C07D 413/06 (2006.01); C07F 9/24 (2006.01);
U.S. Cl.
CPC ...
C07D 203/02 (2013.01); B01J 31/0264 (2013.01); C07D 203/08 (2013.01); C07D 203/14 (2013.01); C07D 203/18 (2013.01); C07D 203/22 (2013.01); C07D 403/04 (2013.01); C07D 413/06 (2013.01); C07F 9/2483 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention relates to methods of synthesizing aziridines including isotopically labelled aziridines, said methods comprising contacting an imine or one or more precursors thereof with a diazo compound in the presence of a phosphoramide or a phosphoramide-derived catalyst. The present invention also relates to aziridines, modified aziridines and aziridine-derived compounds preparable by the aforementioned methods, and to phosphoramide or phosphoramide-derived catalysts suitable for use in such methods.


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