The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

Jul. 27, 2015
Applicant:

The University of British Columbia, Vancouver, CA;

Inventors:

Yu Tian Wang, Vancouver, CA;

Shu Zhang, Vancouver, CA;

Changiz Taghibiglou, Saskatoon, CA;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 9/00 (2006.01); C07K 14/47 (2006.01); A61K 39/395 (2006.01); A61K 47/64 (2017.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 9/0019 (2013.01); A61K 39/3955 (2013.01); A61K 47/645 (2017.08); C07K 14/4702 (2013.01); A61K 38/00 (2013.01);
Abstract

Described herein are isolated polypeptides having phosphatase and tensin homolog (PTEN) inhibitory activity, vectors and cells for the expression thereof and methods for their use in treating diseases associated with cytotoxic stress, such as spinal cord injury, stroke, traumatic brain injury, multiple sclerosis, Alzheimer's disease, amyotrophic lateral sclerosis (ALS), Parkinson's disease, and Huntington's disease.


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