The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

Feb. 22, 2017
Applicants:

Mannkind Corporation, Westlake Village, CA (US);

Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL (US);

Inventors:

Andrea Leone-Bay, Ridgefield, CT (US);

Richard A. Houghten, Vero Beach, FL (US);

Joseph J. Guarneri, Stamford, CT (US);

Grayson W. Stowell, Cary, NC (US);

Assignee:

MannKind Corporation, Westlake Village, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/07 (2006.01); A61K 38/08 (2006.01); A61K 9/14 (2006.01); A61K 38/04 (2006.01); A61K 9/00 (2006.01); A61K 31/495 (2006.01); A61K 31/198 (2006.01); A61K 31/401 (2006.01); A61K 31/405 (2006.01); A61K 47/22 (2006.01); C07K 5/10 (2006.01); C07K 7/06 (2006.01); C07K 5/107 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 9/0075 (2013.01); A61K 9/14 (2013.01); A61K 31/198 (2013.01); A61K 31/401 (2013.01); A61K 31/405 (2013.01); A61K 31/495 (2013.01); A61K 38/04 (2013.01); A61K 38/07 (2013.01); A61K 47/22 (2013.01); C07K 5/10 (2013.01); C07K 5/1016 (2013.01); C07K 7/06 (2013.01);
Abstract

Methods and compositions for treating pain are disclosed. The compositions are based on dry powders comprising microparticles of diketopiperazines and an analgesic active agent. The analgesic in the compositions comprises one or more peptide analgesics or derivatives thereof, which are administered to a subject using a pulmonary inhalation drug delivery system comprising a dry powder inhaler and the analgesic composition. The present compositions produce fewer side effects associated with current opioid therapy.


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