The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

Jul. 17, 2015
Applicant:

Chdi Foundation, Inc., New York, NY (US);

Inventors:

Celia Dominguez, Los Angeles, CA (US);

Ignacio Muñoz-Sanjuán, Los Angeles, CA (US);

Leticia Toledo-Sherman, Santa Monica, CA (US);

Assignee:

CHDI Foundation, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/42 (2006.01); A61K 31/52 (2006.01); A61K 31/70 (2006.01); A61K 31/505 (2006.01); A61K 31/675 (2006.01); A61K 31/506 (2006.01); A61K 31/34 (2006.01); C07D 239/28 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/505 (2013.01); A61K 31/34 (2013.01); A61K 31/506 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07D 239/28 (2013.01);
Abstract

Certain adjunctive therapies comprising a kynurenine-3-monooxygenase inhibitor and an antiviral agent for treating HIV-related disorders are provided herein. These disorders include AIDS dementia complex, AIDS-induced encephalopathy, HIV-associated neurocognitive disorder, asymptomatic neurocognitive impairment, minor neurocognitive disorder, minor cognitive motor disorder, vacuolar myelopathy, peripheral neuropathies, and polymyositis. Also provided are pharmaceutical compositions comprising a kynurenine-3-monooxygenase inhibitor and an antiviral agent.


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