The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

Oct. 07, 2016
Applicant:

Nanoferix, Inc., Nashville, TN (US);

Inventors:

Frantz Le Dévédec, Toronto, CA;

Christine Jane Allen, Toronto, CA;

David M. Stevens, Frederick, MD (US);

Dean James Rager-Aguiar, Spring Hill, TN (US);

Timothy Tordella Ruckh, Mountain View, CA (US);

Carl Eric Elmquist, Franklin, TN (US);

Assignee:

PENDANT BIOSCIENCES, INC., Nashville, TN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/16 (2006.01); A61K 31/122 (2006.01); A61K 31/337 (2006.01); A61K 9/51 (2006.01); A61K 31/573 (2006.01); A61K 31/58 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 9/1641 (2013.01); A61K 9/5031 (2013.01); A61K 9/5146 (2013.01); A61K 31/122 (2013.01); A61K 31/337 (2013.01); A61K 31/573 (2013.01); A61K 31/58 (2013.01);
Abstract

Disclosed are crosslinked particles (e.g., microparticles) that are capable of storing and releasing drugs. The particles can be macroparticles, microparticles, or nanoparticles and can be composed of polyester backbones. The particles can be loaded with a drug. The particles can degrade in vivo to release the drug. The particles can be prepared by crosslinking functionalized polyester backbones and loaded with a given drug. The particles of the present disclosure can be injected with a syringe. In some embodiments, the particles of the present disclosure are administered in connection with a surgery and release the drug after the site of the surgery for a period of 1-6 months.


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