The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

May. 24, 2005
Applicants:

Jacob Mathiesen, Hobro, DK;

Carsten Martini Nielsen, Søborg, DK;

Peder Mohr Olsen, Kirke Hyllinge, DK;

Poul Egon Bertelsen, Roskilde, DK;

Inventors:

Jacob Mathiesen, Hobro, DK;

Carsten Martini Nielsen, Søborg, DK;

Peder Mohr Olsen, Kirke Hyllinge, DK;

Poul Egon Bertelsen, Roskilde, DK;

Assignee:

Takeda AS, Asker, NO;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2077 (2013.01); A61K 9/0056 (2013.01); A61K 9/1623 (2013.01); A61K 9/2004 (2013.01); A61K 9/2018 (2013.01);
Abstract

The present invention relates to a particulate material and a solid dosage form notably tablets comprising a regularly shaped calcium-containing compound such as a calcium salt as a therapeutically and/or prophylactically active substance and a pharmaceutically acceptable sugar alcohol such as, e.g., sorbitol and/or isomalt that has a micro structure as evidenced by SEM. The invention also relates to a process for the preparation of the particulate material and solid dosage form. The process involves agglomeration of the calcium-containing compound and the pharmaceutically acceptable sugar alcohol by means of roller compaction. The particulate material obtained by roller compaction is suitable for use in the further processing of the particulate material into e.g. tablets such as chewing tablets.


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