The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2019
Filed:
Jul. 08, 2015
Applicant:
Amphastar Pharmaceuticals Inc., Rancho Cucamonga, CA (US);
Inventors:
Jeffrey Ding, Rancho Cucamonga, CA (US);
Aili Bo, Rancho Cucamonga, CA (US);
Mary Ziping Luo, Rancho Cucamonga, CA (US);
Jack Yongfeng Zhang, Rancho Cucamonga, CA (US);
Assignee:
Amphastar Pharmaceuticals, Inc., Rancho Cucamonga, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 9/00 (2006.01); A61K 38/28 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1688 (2013.01); A61K 9/008 (2013.01); A61K 9/0075 (2013.01); A61K 9/14 (2013.01); A61K 9/1617 (2013.01); A61K 38/28 (2013.01);
Abstract
A method of preparing an inhalable insulin suitable for pulmonary delivery includes: dissolving an insulin raw material in an acidic solution to form a dissolved insulin solution; titrating the dissolved insulin solution with a buffer solution to form a suspension comprising micronized insulin particles; and stabilizing the micronized insulin particles.