The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

May. 02, 2014
Applicants:

Kullervo Hynynen, Toronto, CA;

Meaghan O'reilly, Toronto, CA;

Foroohar Foroozan, Richmond Hill, CA;

Inventors:

Kullervo Hynynen, Toronto, CA;

Meaghan O'Reilly, Toronto, CA;

Foroohar Foroozan, Richmond Hill, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 8/08 (2006.01); A61B 8/00 (2006.01); G01S 7/52 (2006.01); G01S 15/89 (2006.01);
U.S. Cl.
CPC ...
A61B 8/5238 (2013.01); A61B 8/0891 (2013.01); A61B 8/4494 (2013.01); A61B 8/481 (2013.01); A61B 8/5207 (2013.01); A61B 8/5246 (2013.01); A61B 8/54 (2013.01); G01S 7/52039 (2013.01); G01S 7/52047 (2013.01); G01S 7/52049 (2013.01); A61B 8/0808 (2013.01); G01S 15/8922 (2013.01); G01S 15/8929 (2013.01);
Abstract

Systems and methods for ultrasound imaging capable of achieving spatial resolutions that can resolve objects smaller than 300 μm are described. Ultrasound is transmitted to and steered over a volume-of-interest that contains a microbubble contrast agent to individually excite microbubbles. Signal data is acquired in response to the transmitted ultrasound, and a plurality of images are reconstructed by beamforming the acquired signal data. The spatial resolution of the beamformed images can be further increased using techniques that determine the position of the microbubble within each image to a greater level of accuracy than the point spread function ('PSF') of the ultrasound system. The images can also be combined to produce a single high resolution image of the volume-of-interest using, for instance, a maximum pixel projection technique.


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