The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

Dec. 01, 2015
Applicant:

Koninklijke Philips N.v., Eindhoven, NL;

Inventors:

Ralf Seip, Carmel, NY (US);

William Tao Shi, Wakefield, MA (US);

Assignee:

Koninklijke Philips N.V., Eindhoven, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 8/08 (2006.01); A61B 8/00 (2006.01); A61B 17/22 (2006.01); A61N 7/00 (2006.01); A61B 17/225 (2006.01);
U.S. Cl.
CPC ...
A61B 8/481 (2013.01); A61B 8/085 (2013.01); A61B 8/0808 (2013.01); A61B 8/54 (2013.01); A61B 17/22004 (2013.01); A61N 7/00 (2013.01); A61B 8/587 (2013.01); A61B 17/2256 (2013.01); A61B 2017/22008 (2013.01); A61N 2007/0039 (2013.01); A61N 2007/0052 (2013.01);
Abstract

An ultrasonic intracranial sonothrombolysis pressure amplitude is pre-quantified by using an ultrasound-scanner control unit () having an increasing and/or decreasing mode and designed for: with respect to a current mode, interrogating a blockage site iteratively so as to progressively and respectively increase or decrease a pressure amplitude of ultrasound being emitted to the site at which bubbles () for oscillating that is caused by the emitted ultrasound are present; iteration to iteration, deriving, from echoes of the emitted ultrasound, a magnitude of an energy of a signal; and automatically identifying, for the quantifying, an iteration that, in comparison with a just-previous iteration, fails to increase the magnitude. The interrogating may span a region that contains or goes through: the obstruction; another part of the blood vessel; and bubble circulation within a neighboring vessel and a neighboring capillary (). The deriving can be based on an ultraharmonic signal, with band-pass filtering being utilized to extract the ultraharmonic signal from returning signals differenced to remove stationary content.


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