The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2019

Filed:

Jun. 14, 2018
Applicant:

Endra Life Sciences Inc., Ann Arbor, MI (US);

Inventors:

Jonathan M. Rubin, Ann Arbor, MI (US);

Michael M. Thornton, London, CA;

Aghapi Mordovanakis, Ann Arbor, MI (US);

Assignee:

ENDRA Life Sciences Inc., Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 8/08 (2006.01); A61B 8/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/4872 (2013.01); A61B 5/0035 (2013.01); A61B 5/0095 (2013.01); A61B 5/4244 (2013.01); A61B 5/7246 (2013.01); A61B 5/7485 (2013.01); A61B 8/0858 (2013.01); A61B 8/4416 (2013.01); A61B 8/469 (2013.01); A61B 8/5223 (2013.01); A61B 8/5261 (2013.01); H05K 999/99 (2013.01);
Abstract

A system and method for determining fractional fat content of tissue comprises registering thermoacoustic image coordinates to an acquired ultrasound image, the acquired ultrasound image at least comprising target tissue within a region of interest; defining a thermoacoustic voxel grid coincident with the region of interest; obtaining thermoacoustic image measurement values from tissue within the region of interest corresponding to the voxels within the defined thermoecoustic voxel grid to yield a thermoacoustic measurement matrix; normalizing the thermoacoustic image measurement values within the thermoacoustic measurement matrix; calculating a fractional fat content map for the target tissue within the region of interest based on the normalized thermoacoustic image measurement values within the thermoacoustic measurement matrix and a reference thermoacoustic measurement value; and correcting the fractional fat content map based on tissue speed-of-sound data to yield a final fractional fat content map for the target tissue within the region of interest.


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