The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2019

Filed:

Oct. 01, 2015
Applicants:

Dionex Corporation, Sunnyvale, CA (US);

Thermo Hypersil-keystone Llc, Bellefonte, PA (US);

Inventors:

Xiaodong Liu, Cupertino, CA (US);

Jennifer M. Nguyen, State College, PA (US);

Ronald A. Sherant, Centre Hall, PA (US);

Mark L. Tracy, Sunnyvale, CA (US);

Assignees:

Thermo Hypersil-Keystone LLC, Bellefonte, PA (US);

Dionex Corporation, Sunnyvale, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/56 (2006.01); B01D 15/20 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
G01N 30/56 (2013.01); B01D 15/206 (2013.01); G01N 2030/027 (2013.01); G01N 2030/565 (2013.01);
Abstract

A method of packing a chromatography column, including: dispersing chromatographic media particles in a slurry solution to form a slurry, filling a chromatography column with the chromatographic media particles by introducing the slurry to the column and applying a pressure to pack the chromatographic media particles in the chromatography column. The slurry solution is preferably aqueous based slurry solution. The pressure is preferably applied and held substantially constant for a first period at a first pressure and is applied and held substantially constant for a second period, following the first period, at a second pressure higher than the first pressure.


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