The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2019

Filed:

Mar. 25, 2014
Applicant:

Annikki Gmbh, Graz, AT;

Inventor:

Ortwin Ertl, Vasoldsberg, AT;

Assignee:

ANNIKKI GMBH, Graz, AT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 19/02 (2006.01); C12P 19/24 (2006.01); C07D 307/46 (2006.01); C07D 307/58 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12P 19/02 (2013.01); C07D 307/46 (2013.01); C07D 307/58 (2013.01); C12Y 101/01014 (2013.01); C12Y 101/01307 (2013.01); C12Y 101/01001 (2013.01); C12Y 106/01 (2013.01);
Abstract

Disclosed is a method for the isomerization of glucose by reduction to sorbitol and subsequent oxidation to fructose, in which the redox cofactors NAD/NADH and NADP/NADPH are regenerated in a one-pot-reaction, wherein one of the two redox cofactors is obtained in the reduced form thereof and the other redox cofactor in the oxidized form thereof as a result of at least two additional enzymatically catalyzed redox reactions (product forming reactions) taking place in the same reaction batch, wherein a) in the regeneration reaction, which transfers the reduced cofactor back to its originally oxidized form, oxygen or a compound of the general formula RC(O)COOH is reduced, and b) in the regeneration reaction, which transfers the oxidized cofactor back to its originally reduced form, a compound of the general formula RCH(OH)Ris oxidized, wherein R, Rand Rhave different meanings in the compounds, characterized in that a mixture of glucose and fructose is used as a starting material. Furthermore, the use of fructose thus produced in a method for producing furan derivatives is disclosed.


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