The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2019
Filed:
May. 28, 2015
Applicant:
Greenovation Biotech Gmbh, Freiburg, DE;
Inventors:
Manfred Schuster, Schrick, AT;
Ralf Kircheis, Vienna, AT;
Andreas Nechansky, Oberwaltersdorf, AT;
Wolfgang Jost, Freiburg, DE;
Gilbert Gorr, Freiburg, DE;
Assignee:
GREENOVATION BIOTECH GMBH, Freiburg, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/28 (2006.01); C07K 16/00 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
C07K 16/283 (2013.01); C07K 16/00 (2013.01); C12N 15/8258 (2013.01); C07K 2317/14 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an antigen, characterized in that the antibodies or derivatives or fragments thereof comprise an N-glycan structure free of fucose and xylose, and at least 90%, preferably at least 95%, more preferred at least 99%, most preferred at least 100% of the modified antibodies, derivatives or fragments thereof lack a C-terminal lysine residue.