The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2019
Filed:
Mar. 03, 2015
Universidade DE Vigo, Vigo (Pontevedra), ES;
Universidade DE Santiago DE Compostela, Santiago de Compostela (La Coruña), ES;
Ma del Carmen Terán Moldes, Vigo, ES;
Pedro Besada Pereira, Vigo, ES;
Tamara Costas Caamaño, Vigo, ES;
Ma del Carmen Costas Lago, Vigo, ES;
Noemí Vila Molares, Vigo, ES;
Dolores Viña Castelao, Vigo, ES;
UNIVERSIDADE DE VIGO, Vigo (Pontevedra), ES;
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, Santiago de Compostela (la Coru{umlaut over (n)}a), ES;
Abstract
The present invention refers to pyridazin-3(2H)-one derivatives of general structure I, II and III, which are selective MAO-B inhibitors, and to the use thereof for preparing medicaments intended to treat disorders derived from MAO-B hyperactivity, particularly degenerative disorders of the central nervous system (CNS), such as Parkinson's disease (PD), Alzheimer's disease (AD) and other dementias. These are pyridazin-3(2H)-one derivatives having dithiocarbamate moieties bonded to position 4, 5 or 6 through an alkyl chain of variable length (n=1, 2, 3). This invention is also directed to the preparation of said compounds.